This proposal is to perform some evolutionary studies on the G1PDH from non-rumen archaea and the G1PDH from Methanocaldococcus jannaschii. that has recently been published.  Vince is a young researcher, and it would be get for him to get a Marsden. I have absolutelu no qualms about approving this ROI request. This project would not start until about March 2017, at which point in time the inhibitor programme would have slowed down (the discovery and derivative parts).