This is an invited oral talk to the Sixth International Conference on Sustainable Animal Agriculture for Developing Countries in Indonesia, Oct 16-19th (http://saadc2017.ub.ac.id/ ). I previously gave a talk at this conference series in 2016 in Kuala Lumpur. This talk is similar to the talks recently given at the Chicago Gut Microbiology conference in April and in Japan at a review if NARO programmes at NARO (the Japanese National Agricultural Research Organization) headquarters in Tsukuba, Japan in September.