<p><strong>Aim:</strong> Produce a cost-effective vaccine that reduces ruminant methane emissions by more than 20%</p>
<p><span class="h5">What does success look like?</span></p>
<p>Farmers reducing emissions by vaccination</p>
<p class="h5">How will&nbsp;we get there?&nbsp;</p>
<ol>
<li>Provide proof of concept that methane is reduced by testing in <strong>respiration chambers</strong>.</li>
<li>Confirm the impact and productivity effects</li>
<li>Deliver vaccine to New Zealand market</li>
</ol>
<p class="h5">What&nbsp;input is needed?&nbsp;</p>
<p>Science is needed to develop fundamental science through proof of concept and refinement of final product with commercial partner.&nbsp;</p>
<p>Commercial input it needed to deliver a vaccine to New Zealand and international markets.</p>
<p class="h5">What's the timeline?</p>
<p><img class="mce-popup" title="pipeline_vaccine.jpg" src="user/image/large/439/pipeline_vaccine.jpg" alt="pipeline_vaccine.jpg" width="100%" border="0" data-href="/popup/image/large/439/pipeline_vaccine.jpg" /></p>
<p><img title="pipeline_timeline.jpg" src="user/image/large/435/pipeline_timeline.jpg" alt="pipeline_timeline.jpg" width="100%" border="0" /></p>
<p class="h5">Lead research partner</p>
<p><strong><a href="agresearch.html">AgResearch Limited</a></strong></p>
<p class="h5">Latest progress&nbsp;</p>
<p align="LEFT"><em>"MOST PROMISING PROTOTYPE VACCINES TRIALLED IN SHEEP: The vaccine programme has progressed significantly in the past year. Bioinformatic analysis of genome sequences generated in the methane programme identified and ranked other potential vaccine antigens for testing, greatly increasing the scope for effective vaccine development. Systematic screening of these ranked antigen has commenced. Antigens that induced antibodies that inhibited methanogens in in vitro assays, or resulted in apparent rumen microbial community changes are being evaluated further. Animal trials show that prototype vaccinations can produce high levels of methanogen-specific antibody in the saliva that enter the rumen."</em></p>
<p align="LEFT"><a href="annualreport,listing,209,annual-report-2015.html"><span style="text-decoration: underline;"><strong>Read full annual report</strong></span></a></p>