This conference covers mostly hyperthermophilic microorganisms which are mostly archaea. it is one of three 'Archaea-rich' conference (Archaea, Extremophiles and Thermophiles). This work is almost entirely from the current Marsden grant on methanogen cell wall evolution. The enzyme structure that we will present is very much like its bacterial counterpart and therefore not a good target of inhibitors, but is interesting from an evolution point of view. This is an abstract that will proceed either an oral or poster presentation. 