Note: this manuscript was previously loaded to the ROI on 12 July and a copy also sent to Ashely with updated reporting. I then went on leave and didn't approve as "content owner" so it sat in the system going nowhere. In late September I rejected the submission as "content owner" and uploaded a new version of the manuscript which contained a few changes. I then submitted this via the original ROI request as it appeared this was possible and the process to follow. However, I followed up with Fran on this and was advised that I should copy to a new ROI which I have done here. Hopefully this works. Apologies for not getting this right!